The suggestion of a possible association between diabetes mellitus and chronic HCV infection has revolutionized our recent understanding of non-communicable diseases. The initial idea behind this association was higher prevalence of diabetes mellitus among patients with cirrhosis due to chronic HCV infection compared to those with non-HCV-related cirrhosis (Gane, 2012). However, this was not always true, as some studies did not find an excess prevalence of diabetes mellitus in HCV-infected patients (Marmo, 1998., Imazeki, 2008). This discrepancy is not unexpected, since the prevalence of diabetes in patients with chronic HCV infection may be influenced by several factors such as HCV genotypes, viral load, the severity and duration of liver disease as well as interferon (IFN) therapy (Fenakel, 2000., Ferraz, 2002., Alaei, 2009).
Wednesday, 28 June 2017
Monday, 19 June 2017
The correlation between asthma disease and neutrophil to lymphocyte ratio
Asthma is a chronic inflammatory airway disease that has airway hypersensitivity causing coughing attacks, recurrent wheezing, and dyspnea and that is diagnosed based on anamnesis, spirometric examination, and physiological and pathological characteristics. It is found that its prevalence rate varies based on the countries and between 1% and 18%. Management of asthma, as stated by international guidelines, is based on the assessment of disease control. A useful numerical method to evaluate the level of disease control is the asthma control test (ACT), which includes questions regarding symptoms, medication use, and self-assessed disease control. Pathology of asthma is explained by the fact that numerous inflammatory cells and mediators affect all the airways.
Friday, 9 June 2017
The geo-sanitary conditions of taeniasis carriers, migration and the re emergence of neurocysticercosis
Geo-sanitary conditions in public health are a determining factor in understanding that disease processes are highly dynamic and respond to the conditions of the environmental context. Beyond the biological, immunological and therapeutic scenario in the management of the parasitic diseases which affect the human, the epidemiological conditions that involve the life cycle of the parasite are determinant to the behavior of the disease; such is the case of the Taeniasis and its clinical impact on neurocysticercosis. This is identified punctually how the sanitary conditions can generate the dissemination of the disease by the contamination with feces of human carriers.
Thursday, 1 June 2017
A case of atopic dermatitis that healed completely
The
case, which I wish to demonstrate, is that of a 37-year-old man (H.T.), who
visited my clinic on September 19, 1991. He had had an atopic dermatitis since
the age of 4 years. His dermatitis recovered in part spontaneously at the age of 15 and worsened at the age of 28. He was treated with repeated intra dermal
injections with 1 ampoule of Asthremedin, a product of Nippon Pharmaceutical
Company(Osaka), consisting of 2 mg peptone and extracts of rabbit’s skin and
testis, killed small pox virus, and fungi, at 2-3 day-intervals. Shortly after
the 66th injection, he suffered from a temporary worsening of the dermatitis,
i.e., a considerable quantity of exudes, followed by a complete healing.
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