Hepatitis C-related Diabetes Mellitus: A Health Dilemma Too Necessary to Consider

The suggestion of a possible association between diabetes mellitus and chronic HCV infection has revolutionized our recent understanding of non-communicable diseases. The initial idea behind this association was higher prevalence of diabetes mellitus among patients with cirrhosis due to chronic HCV infection compared to those with non-HCV-related cirrhosis (Gane, 2012). However, this was not always true, as some studies did not find an excess prevalence of diabetes mellitus in HCV-infected patients (Marmo, 1998., Imazeki, 2008). This discrepancy is not unexpected, since the prevalence of diabetes in patients with chronic HCV infection may be influenced by several factors such as HCV genotypes, viral load, the severity and duration of liver disease as well as interferon (IFN) therapy (Fenakel, 2000., Ferraz, 2002., Alaei, 2009).

The correlation between asthma disease and neutrophil to lymphocyte ratio

Asthma is a chronic inflammatory airway disease that has airway hypersensitivity causing coughing attacks, recurrent wheezing, and dyspnea and that is diagnosed based on anamnesis, spirometric examination, and physiological and pathological characteristics. It is found that its prevalence rate varies based on the countries and between 1% and 18%. Management of asthma, as stated by international guidelines, is based on the assessment of disease control. A useful numerical method to evaluate the level of disease control is the asthma control test (ACT), which includes questions regarding symptoms, medication use, and self-assessed disease control. Pathology of asthma is explained by the fact that numerous inflammatory cells and mediators affect all the airways.

The geo-sanitary conditions of taeniasis carriers, migration and the re emergence of neurocysticercosis

Geo-sanitary conditions in public health are a determining factor in understanding that disease processes are highly dynamic and respond to the conditions of the environmental context. Beyond the biological, immunological and therapeutic scenario in the management of the parasitic diseases which affect the human, the epidemiological conditions that involve the life cycle of the parasite are determinant to the behavior of the disease; such is the case of the Taeniasis and its clinical impact on neurocysticercosis. This is identified punctually how the sanitary conditions can generate the dissemination of the disease by the contamination with feces of human carriers.

A case of atopic dermatitis that healed completely

The case, which I wish to demonstrate, is that of a 37-year-old man (H.T.), who visited my clinic on September 19, 1991. He had had an atopic dermatitis since the age of 4 years. His dermatitis recovered in part spontaneously at the age of 15 and worsened at the age of 28. He was treated with repeated intra dermal injections with 1 ampoule of Asthremedin, a product of Nippon Pharmaceutical Company(Osaka), consisting of 2 mg peptone and extracts of rabbit’s skin and testis, killed small pox virus, and fungi, at 2-3 day-intervals. Shortly after the 66th injection, he suffered from a temporary worsening of the dermatitis, i.e., a considerable quantity of exudes, followed by a complete healing.

Incorporation of antigens from whole cell lysates and purified virions from MP12 into fluorescence microsphere immunoassays for the detection of antibodies against Rift Valley fever virus

Rift Valley fever virus (RVFV) is a zoonotic virus belonging to the genus Phlebovirus and one of the five genera in the family Bunyaviridae. In ruminants, the disease is characterized by abortions, fetal deformities, and high mortality rates. Humans are also readily infected through aerosols from infected animals or by exposure to infected animal tissues, aborted foetuses, and from infected mosquitoes. 

RVFV is transmitted among ruminants and humans by direct contact with infectious tissues or by the bites of infected mosquito species of the Aedes and Culex genuses. Global warming has certainly had a great impact on the transmission patterns of RVF. Since the first outbreak in 1930, the geographical distribution of the virus has been expanded to several countries of Africa and the Arabian Peninsula. Now, there are growing concerns of the continued spread of RVF to other parts of the world, including the United States and European Union.

Lymphocyte subset and anti-HLA in AIDS Saudi patients

Human immunodeficiency virus (HIV) infection characterized by profound CD4+ T cell destruction compromised mucosal barrier function and chronic immune activation. In Kingdom of Saudi Arabia (KSA), acquired immune deficiency syndrome (AIDS) considers a significant public health problem. Our study design incorporated sixty-six AIDS Saudi patients under Highly Active Antiretroviral Therapy (HAART1) and after 6-12 months (HAART2), twenty healthy persons as a control. We measure subset lymphocyte cells by flow cytometry, CD3+4+ T cells, CD3+ 8+ T cells, and CD16+/CD56+ ratio were high significantly lower than controls in HARRT1 and HAART2 treatment (P ≤ 0.01). 

COBAS AmpliPrep assessed quantitation of HIV-1 RNA viral load in plasma, also Screening of Human leukocyte antigens antibodies (Panel reactive antibody (PRA)) measured by Luminex 100. There were no significant differences in class I, class II antibodies under the differences between groups, since the indication level value attained (0.311) Chi-square=4.780, and (0.104) Chi-square=4.531 respectively and these values were greater than (0.05) and inconsiderable. Contrary, the results of Class II showed considerable differences antibodies with variable gender. The level value attained (0.008), for study's Saudi women member. The more Immune-biomedical research will be needed in the future to decrease morbidity and mortality in HIV/AIDS patients.

Root tuber of Tacca leontopetaloides L. (kunze) for food and nutritional security

Root and tuber crops provide a substantial part of the world food supply and are also an important source of animal feed and industrial products. On a global basic, approximately 45% of root and tuber crop production is consumed as food, with the remainder used as animal feed or for industrial processing for products such as starch, distilled spirit, alcohol and fermented beverages including beer and a range of minor products. Millions of people in many developing countries do not have enough food to meet their daily requirements and many more are deficient in one or more micronutrients. In many cases rural communities depend on wild resources including wild edible plants to meet their food needs in periods of food shortage.